| Wk | Date & Time | Away | Home | TV | ||||
|---|---|---|---|---|---|---|---|---|
| 01 | Sun Feb 19 8:00PM ET |  | Seattle Sea Dragons 18 | @ |  | D.C. Defenders 22 | ESPN, ESPN+ | Game Summary |
| 02 | Sat Feb 25 7:00PM ET | | D.C. Defenders 18 | @ |  | Vegas Vipers 6 | FX, ESPN+ | Game Summary |
| 03 | Sun Mar 5 1:00PM ET |  | St. Louis Battlehawks 28 | @ | | D.C. Defenders 34 | FX, ESPN+ | Game Summary |
| 04 | Sun Mar 12 7:00PM ET | | Vegas Vipers 18 | @ | | D.C. Defenders 32 | ESPN2, ESPN+ | Game Summary |
| 05 | Sat Mar 18 7:00PM ET | | D.C. Defenders 28 | @ | | St. Louis Battlehawks 20 | FX, ESPN+ | Game Summary |
| 06 | Mon Mar 27 7:00PM ET |  | Houston Roughnecks | @ | | D.C. Defenders | ESPN2, ESPN+ | Ticketmaster StubHub |
| 07 | Sat Apr 1 6:00PM ET | | D.C. Defenders | @ |  | Orlando Guardians | ESPN, ESPN+ | Ticketmaster StubHub |
| 08 | Sun Apr 9 7:00PM ET | | D.C. Defenders | @ | | Seattle Sea Dragons | ESPN2, ESPN+ | Ticketmaster StubHub |
| 09 | Sun Apr 16 12:00PM ET |  | Arlington Renegades | @ | | D.C. Defenders | ESPN, ESPN+ | Ticketmaster StubHub |
| 10 | Sat Apr 22 3:00PM ET | | D.C. Defenders | @ |  | San Antonio Brahmas | ABC, ESPN+ | Ticketmaster StubHub |